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KMID : 0615720010180010217
Jouranl of Korean Acupuncture and Moxibustion society
2001 Volume.18 No. 1 p.217 ~ p.225
Effect of Strychni Semen Aqua - acupuncture in Rats with Arthritis induced by Freund`s Complete Adjuvant




Abstract
Objectives and Mtthods : In order to study on the Effect of Strychni Semen aqua-acupuncture on the arthritis induced by injecting Freund¢¥s complete adjuvant to the right posterior planta of rat¢¥s foot, rats were divided 5 groups equally, one group was not treated(Normal) and the other groups were induced arthritis by injecting Freund¢¥s complete adjuvant(Control, ST, SS, SST). Control was not treated after injecting of Freund¢¥s complete adjuvant. ST was 0.2cc Saline-injected Group at Chok-Samni(ST36) either days during 2 weeks after injecting of Freund¢¥s complete adjuvant. SS was 0.2cc Strychni Semen-subcutaneous injected group either days during 2 weeks after injecting of Freund¢¥s complete adjuvant. SST was 0.2cc Strychni Semen-injected group at Chok-Samni(ST36) either days during 2 week after injecting of Freund¢¥s complete adjuvant. And then effect of Strychni Semen aqua-acupuncture on the edema, numbers of blood WBC, platelet, hematocrit, contented quantities of total protein, albumin in rats with F.C.A were measured.
Results : The following results have been obtained.
1. In effect of Strychni Semen aqua-acupuncture on plantar edema, SS showed significant decrease compared with control.
2. In effect of Strychni Semen aqua-acupuncture on WBC, SS and SST showed significant decrease compated with control.
3. In effect of Strychni Semen aqua-acupuncture on platelet, SS and SST did not show significant decrease.
4. In effect of Strychni Semen aqua-acupuncture on hematocrit, SST showed significant increase compared with control.
5. In effect of Strychni Semen aqus-acupuncture on the contents quantity of total protein and albumin, SS showed significant increase compared with control:
Conclusions : Accoring to this result, Strychni Semen aqua-acupunture inserted into Chok-Samn i(ST36) appeared to have effect on Adjuvant arthritis of rats. Therefore it is oxpected that Strychni Semen aqua-acupunture may be available clinically.
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